7 Hottest Python Frameworks To Use In 2022

February 3, 2022

Why is Python the best programming language for ML? Why is it so popular in Industry 4.0? Python is the fastest-growing programming language in the world. It is readable and an easy-to-use programming language that developers use for data science, blockchain, NLP, neural networking, scientific computing and other dynamic projects.

Despite the huge developer community, Python is still growing and offers a plethora of frameworks for web development. In this article, we are going to throw light on the 7 hottest frameworks of 2022.

Without further ado, let’s get started!

Python Development Frameworks To Use In 2022


Django makes it to the top in our list of Python development frameworks. First released in 2005, it is one of Python’s oldest and most popular frameworks.

A free and open-source Python framework, Django enables the developers to build complex code and applications quickly. It assists in reducing the development time and building APIs for different web applications.

This is a high-level framework that streamlines all the web application development by offering plenty of features. Offering a plethora of libraries, this framework reduces the need for rigorous coding and makes effective component reusability.

Key Features:

  • Helps define the patterns of the URLs in your application
  • A powerful built-in authentication system
  • Powerful URL system
  • OOP language database that offers the best recovery and data storage
  • An automatic admin interface enables modifying and deleting different elements
  • Cache framework offers multiple cache mechanisms


The Pyramid framework is versatile and the developers use it for different projects with specific requirements. It is the most valued web framework among the developers and offers quality and transparency. Pyramid is used by tech giants like Yelp, Dropbox, Mozilla and more.

Merger of the repoze.bfg and Pylons, Pyramid is a simple to use web framework that aims at streamlining the work of developers. Pyramid is quite a mature feature-rich Python web framework. It has a wide range of uses including websites, web APIs and anything you would expect from a popular Python framework.

Key Features:

  • Allows developers to run with both small and large applications.
  • Offers mapping based on URL dispatching
  • Offers HTML structure generation and validation
  • Complete support, testing, and data documentation
  • Authentication & approval


CherryPy is one excellent example of a Python framework that is used as the foundation of several web applications. It is an open-source Python web development framework that embeds its multi-hung server making, it runs on any framework that supports Python. A big selling point of CherryPy is that it allows the users to run their code without relying on other services or developers. Your developers can easily deploy an application using only the components found within this framework.

Key Features:

  • Offers a consistent WSGI thread-pooled web server that is HTTP/1.1-compliant
  • Compatible with various HTTP servers on multiple ports
  • Supports Python 2.7+, 3.5+, Android, PyPy, & Jython
  • Offers plenty of built-in tools for sessions, authentication, caching, static content, encoding, & many more
  • Offers a powerful configuration system for developers and deployers alike
  • Built-in testing support, coverage and profiling


Flask is a python framework that is accessible under the BSD license. This framework relies upon the Werkzeug WSGI toolbox and Jinja2 template. The main purpose of Flask is to assist the developers to build dynamic web applications.

Developers can develop their Python-backend framework using Flask. This framework is best suited for small and easy-to-do projects. Flask is one of the most popular web Python frameworks and is a fast-growing tool. It is simple to learn, easy to use, and has an extensive library of add-ons. Being easy to deploy, its popularity stems from the simplicity it offers.

Key Features:

  • Offers built-in debugger and development server
  • Request dispatching for RESTful APIs
  • Offers integrated unite testing support
  • It is 100% WSGI 1.0 compliant
  • Uses Jinja2 templating feature for filters, tags, macros and more


Bottle is a WSGI (web server gateway interface) that is simple, fast and lightweight. It is also distributed as a simplified module and requires only the Python standard library. The features this framework offers are much similar to that of Flask which makes switching between the different frameworks smooth.

Bottle offers tons of functionalities:

  • Templating
  • Directing
  • Utilities
  • Fundamental abstraction over the WSGI standard

It offers tons of features in a single file with no dependencies other than the standard library. If you want to create a landing page quickly or add some quick prototyping capabilities then this is the framework you should select.


Web2py offers a complete suite that comprises a debugger, code editor, and a deployment tool. This suite enables the developers to debug the code and keep up with the web application development. It is a cross-platform platform that supports Unix/Linux, Mac, Google App Engine and several other platforms.

Web2Py streamlines Python development procedures through a web server, SQL database, and an online interface. This framework enables the clients to build, deploy, revise and manage web applications through web browsers.

Key Features:

  • Speeds up web development
  • Streamlines web development through MVC architecture
  • Enables the developers to work with NoSql and relational databases.
  • Offers a web-based IDE to accelerate different functions like editing app files, running tests, browsing the old tickets, and cleaning the temporary files
  • Safeguard the web applications by addressing the top vulnerabilities and security issues


A data-driven full-stack web application Python framework, TurboGears is designed to overcome the efficiencies of various extensively used web and mobile app development frameworks. It empowers the software developers to begin the development process with an insignificant setup.

You can easily develop web applications with the help of Repoze, WebOb, Genshi, SQLAlchemy which are much faster than the other existing frameworks. TurboGears operates in an MVC environment and incorporates vigorous formats, AJAX for server programs and an incredible Object Relational Mapper (ORM).

Key Features:

  • It enables the developers to execute all features as function decorators
  • Offers multi-database support
  • Easy access to command-line tools and utilities
  • Offers Mochikit JavaScript library integration
  • Offers MVC-style architecture and PasteScript templates
  • Ease the coordination of frontend design and server deployment using the Toscawidgets


Although several Python web development frameworks are popular and are in demand in the coming years, every framework is different in its cons and pros. The choice of a Python development framework depends on the specific project requirements and the Python website development team you have.

In this blog, we have discussed the popular Python frameworks to use in 2022. Get in touch with a proficient tech partner for faster product launches. DRC Systems is a Python development company and we have been assisting several businesses across the globe. Hire dedicated Python developers and get the most out of your business idea. If you are planning to build microservices with Python, give DRC Systems a try. Contact us today!


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